If in utero constriction is detected during an ultrasound, it is often possible to treat it by performing prenatal surgery. In particular, the ultrasound will look for any areas of potential constriction inside the womb that could cause a limb to fail to grow. The ultrasound will attempt to identify whether limbs are missing or there are other congenital defects in organs or body systems. Typically, testing will use ultrasonography to look at the fetus's developing body. However, if a parental medical history discloses that there has been exposure to the class of toxins known as teratogens (toxins that can cause harm to a fetus), then prenatal diagnostic procedures may be recommended. This is because in many cases, amelia may not be suspected, so special prenatal testing will not look for the condition. At times, idiopathic amelia happens and no causes can be specifically identified.ĭiagnosis of amelia often will not occur until the day of delivery. In many cases (an estimated 50 percent of the time), amelia occurs when there is already malformation or deformity in one or more major organs. If for any reason there is a constriction that develops inside the womb, this can cause a limb to fail to form. If the mother has gestational diabetes, this can cause amelia. If the mother is exposed to certain toxins, such as thalidomide or alcohol, amelia may result in the fetus.
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